With the Desmo450 MX, Ducati presents the first motocross bike in the brand's history. It was developed with the goal of transferring technologies from racing into a new market segment. According to Ducati, the development approach follows the tradition of first testing innovative solutions on the race track. The Desmo450 MX is said to incorporate insights gained from MotoGP and the Superbike World Championship.
The bike was created in collaboration with Team Maddii Racing. The concept was presented in 2024 and was already used that same year in the Italian motocross championship, including by Alessandro Lupino and Tony Cairoli. Production starts in April 2025, with the market launch in June in Europe, followed by North America and other regions.

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